During musculoskeletal surgery, an undefined mixture of bone marrow, cancellous bone fragments, fat, hematoma and additional soluble factors occur at the bony implant site. Together with inflammatory cytokines and nervous stimuli, this microenvironment includes a strong osteogenic potential, associated with an increased risk for ectopic bone formation (non-hereditary heterotopic ossification).
Usually, this „bone stew“ is being collected in a plastic-filter of conventional suction handles and later disposed.
Meanwhile, recent research data suggests that the collected surgical-site released tissue is able to enhance local osteoinduction.
These newly identified tissue characteristics were designated „osteopromotive“ and led to the BoneFlo® Concept.